Achieving Rapid LC-MS Analyses Using Avantor® ACE® HTP-MS Columns
Achieving fast LC analyses is essential in high sample throughput laboratories, such as clinical, drug discovery and environmental labs. Over the last two decades, UHPLC has enabled many labs to dramatically increase sample throughput, through use of shorter columns packed with sub-2 micron particles. However, at the same time, the performance of modern mass spectrometers has continued to evolve. Improved sensitivity and ultra-fast data acquisition capabilities, provide opportunities to further reduce analytical run times, using specially designed, high throughput columns.
This webinar begins by discussing the concepts of how to develop high throughput LC-MS methods, before introducing the Avantor® ACE® HTP-MS column. The use of this column format to develop ultra-fast LC-MS analyses will be discussed, along with several key applications that demonstrate the advantages that can be realised. Finally, some of the challenges associated with rapid analysis will be discussed, including aspects of sample preparation and the impact the matrix can have on the detector.
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